Between Science and Community: development and validation of an educational booklet on early diagnosis of Autism Spectrum Disorder and molecular biomarkers
DOI:
https://doi.org/10.1590/SciELOPreprints.17033Keywords:
Autism Spectrum Disorder, microRNAs, Health EducationAbstract
Autism Spectrum Disorder (ASD) is a neurodevelopmental condition with an estimated prevalence of 1.1% of the population. In Mato Grosso do Sul, Brazil, more than 29,000 cases are estimated, although many remain underreported due to diagnostic barriers. This study describes the development and validation of an educational guide that integrates scientific communication on salivary biomarkers (microRNAs) with community engagement in translational research. Validation of the educational guide involved15 health and education professionals and 8 members, formed by caregivers, family members, and adults with ASD. The Content Validity Index (CVI) was used for this purpose. All items achieved a CVI > 0.80. This guide constitutes an important instrument for scientific communication on ASD, democratization of knowledge, and community engagement in research.
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Copyright (c) 2026 Julia Cunha Gonzales, Marcos Fernandes Morales, Rômulo Diniz de Arruda, Willy Rilston Souza de Jesus, Alinne Pereira de Castro
This work is licensed under a Creative Commons Attribution 4.0 International License.
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Data statement
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The research data cannot be made publicly available
- All data generated or analyzed during this study are included in this manuscript and its supplementary figures. The raw data from the validation questionnaire are not publicly available to preserve participant anonymity, as approved by the Research Ethics Committee of Dom Bosco Catholic University (CAAE: 56241522.9.0000.516).
