Associação do transtorno depressivo maior com doenças crônicas e multimorbidade em adultos brasileiros, estratificada por sexo: Pesquisa Nacional de Saúde 2019

Neuciani Ferreira da Silva Sousa; Marilisa Berti de Azevedo Barros; Lhais de Paula Barbosa Medina; Deborah Carvalho Malta; Celia Landmann Szwarcwald

doi:10.1590/1980-549720210015.supl.2

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Neuciani Ferreira da Silva Sousa Universidade Federal de Mato Grosso, Cuiabá (MT), Brasil https://orcid.org/0000-0002-7694-0811
Marilisa Berti de Azevedo Barros Universidade Estadual de Campinas - Campinas (SP), Brasil
Lhais de Paula Barbosa Medina Universidade Estadual de Campinas - Campinas (SP), Brasil
Deborah Carvalho Malta Universidade Federal de Minas Gerais – Belo Horizonte (MG), Brasil
Celia Landmann Szwarcwald Fundação Oswaldo Cruz – Rio de Janeiro (RJ), Brasil

DOI:

https://doi.org/10.1590/1980-549720210015.supl.2

Keywords:

Depressive Disorder, Chronic Disease, Multimorbidity, Health Surveys

Abstract

Objective: To analyze the association of major depressive disorder (MDD) with the presence of chronic non-communicable diseases (CNCD) and multimorbidity in Brazilian adults, stratified by sex, and to examine the interaction between sex and CNCD in association with TDM. Methods: Based on a sample of 65,803 adults from the National Health Survey of 2019, the prevalence of MDD (≥ 10 points of the PHQ-9 instrument) was estimated according to the presence of CNCD and multimrbity (≥ 2 chronic diseases). The prevalence ratios and respective confidence intervals were estimated using Poisson regression and the terms of multiplicative interaction were used to assess the role of sex in associations. Results: The prevalence of MDD among Brazilian adults (18-59 years) was estimated at 10.9%, with a statistically significant difference between men (6.0%) and women (15.4%) (p <0.001). Among individuals with any CNCD and multimorbidity, higher prevalence of MDD was observed, both in the general population and in both sexes. However, the association between TDM and NCDs tended to be stronger among men. The data also showed an interaction between male gender and multimorbidity or specific diseases such as arthritis or rheumatism, heart disease and chronic renal failure in association with MDD. Conclusion: The results show a significant association between TDM and NCD, in both sexes, and raise the hypothesis that the effect of multimorbidity and specific diseases may be greater on the mental health of men.