Preprint / Version 1

Screening of Vertical Transmission of Chagas Disease in the Federal District: an Action to Restructure Surveillance

##article.authors##

  • Gizeli de Lima Pedroso Gonçalves Secretaria de Estado de Saúde do Distrito Federal
    • Daphne Rattner University of Brasília image/svg+xml https://orcid.org/0000-0003-1354-9521
      • Ana Claudia Morais Godoy Figueiredo Secretaria de Estado de Saúde do Distrito Federal
        • Aline Duarte Folle Secretaria de Estado de Saúde do Distrito Federal
          • Fernanda Souza Nogueira Sardinha Mendes Instituto Nacional de Infectologia Evandro Chagas -INI, Fiocruz-RJ https://orcid.org/0000-0003-2033-1715

            DOI:

            https://doi.org/10.1590/SciELOPreprints.12442

            Keywords:

            Chagas disease, Vertical transmission of infectious diseases, Trypanosoma cruzi, Congenital infection

            Abstract

            This study aimed to analyze the epidemiological situation of children born to mothers diagnosed with Chagas disease (CD) during prenatal care in the Federal District (FD), from 2017 to 2021. It is a quantitative, descriptive, and cross-sectional study based on secondary data from the State Health Department of the FD. A total of 162 women with chronic CD were identified (prevalence of 7.8/10,000 live births), resulting in 278 pregnancies and 223 live births. Of these, 54.7% were diagnosed during prenatal care, but 68.5% (n=61) reported not receiving guidance on the risk of vertical transmission. During the survey, 85.1% (n=172) of the children were tested, but only 10.8% (n=24) had been previously screened for CD. In total, 16.3% (n=33) were classified as suspected vertical transmission cases, with underreporting observed in the official system. No confirmed vertical transmission occurred during the period; however, one five-year-old child was diagnosed with the infection. The findings highlight the need to strengthen surveillance, improve timely case reporting, and ensure proper screening and follow-up for children born to mothers with CD to reduce underreporting and increase access to early diagnosis and treatment when necessary.

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            Posted

            07/17/2025

            How to Cite

            Screening of Vertical Transmission of Chagas Disease in the Federal District: an Action to Restructure Surveillance. (2025). In SciELO Preprints. https://doi.org/10.1590/SciELOPreprints.12442

            Section

            Health Sciences

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            Data statement

            • The research data is contained in the manuscript