ARE SUPERFICIAL SERRATED LESIONS IN EARLY STAGES HYPERPLASTIC OR SESSILE SERRATED LESIONS?

Matheus Degiovani; Osvaldo Malafaia; Artur Adolfo Parada; Fernando Issamu Tabushi; Marcos Fabiano Sigwalt; Paulo Afonso Nunes Nassif; Luiz Martins Collaço; Cláudio Luciano Franck

doi:10.1590/SciELOPreprints.8352

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Matheus Degiovani Faculdade Evangélica Mackenzie do Paraná
Osvaldo Malafaia Faculdade Evangélica Mackenzie do Paraná
Artur Adolfo Parada Center for Endoscopic Diagnosis and Therapeutics of São Paulo
Fernando Issamu Tabushi Faculdade Evangélica Mackenzie do Paraná
Marcos Fabiano Sigwalt Faculdade Evangélica Mackenzie do Paraná
Paulo Afonso Nunes Nassif Faculdade Evangélica Mackenzie do Paraná https://orcid.org/0000-0002-1752-5837
Luiz Martins Collaço Faculdade Evangélica Mackenzie do Paraná
Cláudio Luciano Franck Faculdade Evangélica Mackenzie do Paraná

DOI:

https://doi.org/10.1590/SciELOPreprints.8352

Keywords:

Colorectal neoplasms, Adenocarcinoma, Colon, Rectum

Abstract

BACKGROUND: At least 20% of colorectal adenocarcinomas arise through serrated lesions and studying them in early stages is important in prevention.

AIM: To analyze and compare the endoscopic and histopathological characteristics of superficial serrated lesions in early stages, greater than 5 mm in length, completely resected during colonoscopies, and classified.

METHOD: Retrospective and observational study evaluating 12,653 colonoscopy exams where 217 cases were selected that underwent endoscopic resections of superficial serrated lesions measuring more than 5 mm in diameter, addressed in terms of anatomical location, endoscopic findings, the average size of the lesions, average age, gender, and anatomopathological result.

RESULTS: There were 2 groups G1 and G2. G1 had 126 hyperplastic lesions (HL) and G2 had 91 sessile serrated lesions. The anatomical location was 57.9% proximal and 42.1% distal in G1 and 94.5% and 5.5% respectively in G2. In G1, type 0-IIa was found in 26.2% and lateral spreading in 73.8%; in G2, 15.4% and 84.6%, respectively. The average size of the lesions in G1 was 15.4 mm and in G2, 16.7 mm. The average age G1 was 62.6 and G2, 63.5. Women were predominant in the total number of patients. No invasive adenocarcinomas were observed in the 2 groups.

CONCLUSIONS: Superficially elevated serrated lesions, measuring more than 5 mm and resected by colonoscopies, were hyperplastic (58%). HL was observed throughout the colon and rectum and SSL was predominantly in the proximal colon. HL did not present dysplasia and SSL did. No invasive adenocarcinomas were observed in the submucosa.