CHARACTERIZATION OF CLINICAL AND PARACLINICAL VARIABLES AND THEIR ASSOCIATION WITH THE MAIN MATERNAL OUTCOMES IN PREGNANT WOMEN WITH SEVERE PREECLAMPSIA DURING TWO YEARS AT THE UNIVERSITY HOSPITAL OF NEIVA.

Abstract

Preeclampsia is a disease of pregnancy that manifests after 20 weeks. Its diagnosis is determined by hypertension plus proteinuria, establishing severity with: blood pressure ≥ 160/110 mmHg, symptoms and signs of vasospasm or paraclinical alterations. The University Hospital of Neiva is the main reference center in the Colombian South, where preeclampsia is a reason for referral. We don´t have a study that allows us to know the clinical and paraclinical characteristics and their association with the maternal outcomes of pregnant women with severe preeclampsia.

Methodology: Descriptive observational study of cross-sectional cohort. Characterized clinical and paraclinical variables and their association with the main maternal outcomes. Results: 334 mothers with a singleton pregnancy and severe preeclampsia were included. 77.6% were between 17 and 34 years old, 97.6% in strata 1 and 2, urban origin in 78% and 65.3% multi-pregnant. In addition, 60.8% with obesity. Regarding paraclinical findings, 35.9% with positive proteinuria, 5% thrombocytopenia, elevated serum creatinine (5%), 27% with elevated transaminases and elevated lactic dehydrogenase (3.6%). 55.6% had a preterm pregnancy and 90% of them were terminated by caesarean section. Complications were hypertensive crisis in 59%, acute kidney injury (5%), HELLP syndrome (3.6%), eclampsia (1.2%), and disseminated intravascular coagulation (1.2%). Conclusion: A population with socioeconomic vulnerability was evidenced, aged between 17 and 34 years, mainly obese, with late presentation of the disease; highlighting the development of hypertensive crisis, elevation of transaminases and completion route by cesarean section.