PODEM A TROPONINA SANGUÍNEA E SALIVAR SER SINALISADORAS PRECOCES DO INFARTO AGUDO DO MIOCÁRDIO?

Flávia Kubrusly Arsego; Luiz Fernando Kubrusly; Douglas Mesadri Gewehr; Rafael Dib Possiedi; Paulo Afonso Nunes Nassif; Fernando Issamu Tabushi; Fernando Bermudez Kubrusly; Maria Luiza Ronkoski; Priscila Panassolo Cioato

doi:10.1590/SciELOPreprints.8269

##article.authors##

Flávia Kubrusly Arsego Faculdade Evangélica Mackenzie do Paraná, Curitiba, PR, Brasil
Luiz Fernando Kubrusly Faculdade Evangélica Mackenzie do Paraná
Douglas Mesadri Gewehr Faculdade Evangélica Mackenzie do Paraná, Curitiba, PR, Brasil
Rafael Dib Possiedi University of Toronto
Paulo Afonso Nunes Nassif Faculdade Evangélica Mackenzie do Paraná, Curitiba, PR, Brasil https://orcid.org/0000-0002-1752-5837
Fernando Issamu Tabushi Faculdade Evangélica Mackenzie do Paraná, Curitiba, PR, Brasil
Fernando Bermudez Kubrusly Faculdade Evangélica Mackenzie do Paraná, Curitiba, PR, Brasil
Maria Luiza Ronkoski Faculdade Evangélica Mackenzie do Paraná, Curitiba, PR, Brasil
Priscila Panassolo Cioato Faculdade Evangélica Mackenzie do Paraná, Curitiba, PR, Brasil

DOI:

https://doi.org/10.1590/SciELOPreprints.8269

Keywords:

Troponin I, Troponin T, Acute myocardial infarction

Abstract

Introduction: Myocardial injury can be identified by biomarkers extracted from cardiac cells. Troponin is one of them and can be observed in blood and saliva. Saliva is preferred due to its ease of non-invasive and pre-hospital collection.

Objective: To review whether the expression of troponin I in salivary fluid in acute myocardial infarction in emergency screening is viable compared to its plasma levels.

Method: The literature review was carried out by collecting information published in SciELO, Bibliomed, VHL - Biblioteca Virtual em Saúde, Pubmed and Scopus in Portuguese and English. The search was based on descriptors related to the topic, identified as: “troponin, acute myocardial infarction, cardiac biomarkers, salivary fluid”, with AND and OR searches.

Results: Were included 109 articles correlated to the theme.

Conclusion: Diagnosis based on saliva offers many options and could be a very interesting option for elucidating acute myocardial infarction for general practitioners, nursing homes and transport services quickly, aiding early treatment.