Progress in Alzheimer’s disease therapy

Nelson Durán; Wagner Fávaro; Gerson  Nakazato

doi:10.1590/SciELOPreprints.14301

##article.authors##

Nelson Durán State University of Campinas (UNICAMP) https://orcid.org/0000-0001-8372-5143
- Conceptualization
- Data Curation
- Formal Analysis
- Investigation
- Methodology
- Validation
- Writing – Original Draft Preparation
- Writing – Review & Editing
Wagner Fávaro State University of Campinas (UNICAMP) https://orcid.org/0000-0001-5830-8938
- Investigation
- Methodology
- Validation
- Visualization
- Project Administration
- Writing – Original Draft Preparation
- Writing – Review & Editing
Gerson Nakazato Londrina State University https://orcid.org/0000-0001-8624-795X
- Investigation
- Formal Analysis
- Project Administration
- Supervision
- Validation
- Visualization
- Writing – Original Draft Preparation
- Writing – Review & Editing

DOI:

https://doi.org/10.1590/SciELOPreprints.14301

Keywords:

Dementia, Alzheimer, immunotherapy, biomarker

Abstract

The present article points out dementia diagnosis, dementia mechanisms, advancements in Alzheimer's disease therapy, symptom management, lifestyle and non-pharmacological mediations, genetic and biomarker research, pathophysiological aspects, biomarkers, new drug release systems, neuroprotective agents, and several aspects of immunotherapy and gene treatment. Data on these topics have led to the conclusion that although it was not possible to cure this disease through chemotherapy, significant progress was found in it. According to this review, new therapies featured by extreme efficiency, low toxicity and low-cost feasibility will soon come up.