Preprint / Version 1

CHARLSON'S COORDINITY INDEX IN SYSTEMIC LUPUS ERYTHEMATOSUS IN BRAZILIAN PATIENTS

##article.authors##

  • Fernando Filipini Faculdade Evangélica Mackenzie do Paraná, Curitiba, PR, Brasil
  • Giuli Andretta Faculdade Evangélica Mackenzie do Paraná, Curitiba, PR, Brasil
  • Thiago Alberto Santos Faculdade Evangélica Mackenzie do Paraná, Curitiba, PR, Brasil
  • Ronaldo Mafia Cuenca University of Brasília image/svg+xml
  • Orlando Jorge Martins Torres Federal University of Maranhão image/svg+xml
  • Nelson Adami Andreollo Universidade Estadual de Campinas image/svg+xml
  • Thelma Larocca Skare Faculdade Evangélica Mackenzie do Paraná https://orcid.org/0000-0002-7699-3542

DOI:

https://doi.org/10.1590/SciELOPreprints.6707

Keywords:

Lupus erythematosus, systemic, Survival, Charlson’s comorbidities index, Prognosis

Abstract

Introduction: The Charlson comorbidities index (CCI) assesses a person's chances of survival over the next 10 years. In systemic lupus erythematosus (SLE), multiple comorbidities and complications affect patient survival. Objetive: Analize the variables that influence the CCI of a group of females with SLE. Methods: Retrospective study of medical records of 100 lupus patients for CCI, clinical, epidemiological and serological variables. Results: No epidemiological variable interfered in CCI. Regarding clinical manifestations, patients with glomerulonephritis had a worse CCI than those without (p<0.0001) and those with central nervous system manifestations had a tendency to worse CCI (p=0.09). Patients with anti-Ro antibodies (p=0.02) and rheumatoid factor or RF (p=0.002) were associated with a lower CCI. Conclusions: The presence of glomerulonephritis is associated with lower survival and of the anti-Ro and RF antibodies with longer survival in SLE.

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Posted

08/30/2023

How to Cite

Filipini , F., Andretta, G., Santos, T. A., Cuenca, R. M., Torres, O. J. M., Andreollo , N. A., & Skare, T. L. (2023). CHARLSON’S COORDINITY INDEX IN SYSTEMIC LUPUS ERYTHEMATOSUS IN BRAZILIAN PATIENTS. In SciELO Preprints. https://doi.org/10.1590/SciELOPreprints.6707

Section

Health Sciences

Plaudit

Data statement

  • Data statement is contained in the manuscript