CHARLSON'S COORDINITY INDEX IN SYSTEMIC LUPUS ERYTHEMATOSUS IN BRAZILIAN PATIENTS
DOI:
https://doi.org/10.1590/SciELOPreprints.6707Keywords:
Lupus erythematosus, systemic, Survival, Charlson’s comorbidities index, PrognosisAbstract
Introduction: The Charlson comorbidities index (CCI) assesses a person's chances of survival over the next 10 years. In systemic lupus erythematosus (SLE), multiple comorbidities and complications affect patient survival. Objetive: Analize the variables that influence the CCI of a group of females with SLE. Methods: Retrospective study of medical records of 100 lupus patients for CCI, clinical, epidemiological and serological variables. Results: No epidemiological variable interfered in CCI. Regarding clinical manifestations, patients with glomerulonephritis had a worse CCI than those without (p<0.0001) and those with central nervous system manifestations had a tendency to worse CCI (p=0.09). Patients with anti-Ro antibodies (p=0.02) and rheumatoid factor or RF (p=0.002) were associated with a lower CCI. Conclusions: The presence of glomerulonephritis is associated with lower survival and of the anti-Ro and RF antibodies with longer survival in SLE.
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Copyright (c) 2023 Fernando Filipini , Giuli Andretta, Thiago Alberto Santos, Ronaldo Mafia Cuenca, Orlando Jorge Martins Torres, Nelson Adami Andreollo , Thelma Larocca Skare

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