Intervalos de referência de hemograma da população adulta brasileira: Pesquisa Nacional de Saúde

Ana Carolina Micheletti Gomide Nogueira de Sá; Nydia Strachman Bacal; Crizian Saar Gomes; Tércia Moreira Ribeiro da Silva; Renata Patrícia Fonseca Gonçalves; Deborah Carvalho Malta

doi:10.1590/1980-549720230004.supl.1.1

##article.authors##

Ana Carolina Micheletti Gomide Nogueira de Sá Universidade Federal de Minas Gerais https://orcid.org/0000-0002-0122-2727
Nydia Strachman Bacal Centro de Hematologia de São Paulo
Crizian Saar Gomes Universidade Federal de Minas Gerais
Tércia Moreira Ribeiro da Silva Universidade Federal de Minas Gerais
Renata Patrícia Fonseca Gonçalves Universidade Federal dos Vales do Jequitinhonha e Mucuri
Deborah Carvalho Malta Universidade Federal de Minas Gerais

DOI:

https://doi.org/10.1590/1980-549720230004.supl.1.1

Keywords:

Health Surveys, Reference Values, Blood Cell Count, Leukocytes, Brazil

Abstract

Objective: to estimate the reference intervals (RIs) of complete blood count parameters in the Brazilian adult population. Methods: Cross-sectional study, with data from the National Health Survey (PNS), between 2014-2015. The final sample consisted of 2,803 adults. The final sample consisted of 2,803 adults. To establish the RI, exclusion criteria were applied, outliers were removed and partitions were made by sex, age and race/skin color. The non-parametric method was adopted. Differences were assessed using the Mann Withney and Kruskal Wallis tests (p≤0.05). Results: There were statistically significant differences for the following hematological parameters based on sex, red blood cells, hemoglobin, hematocrit, MCH, MCHC, eosinophils and absolute monocytes, neutrophils and platelets (p≤0.05). When analyzed by age, the RIs were statistically different in females for hematocrit, MCV, white blood cells and RDW and in males for red blood cells, white blood cells, eosinophils, mean platelet volume, MCV, RDW and MCH(p≤0.05). For race/color there were differences in the RIs for parameters of hemoglobin, MCH, MCHC, white blood cells and mean platelet volume, neutrophils and absolute eosinophils (p ≤ 0.05). Conclusion: The differences found in the RIs of some in blood count parameters in Brazilian adults reaffirm the importance of having their own laboratory reference standards. The results can support a more accurate interpretation of tests, adequate identification and disease prevention in Brazil.