Prevalence and factors associated with SARS-CoV-2 infection: a serial population-based study in Espírito Santo, Brazil, May to June 2020

Abstract

Objective: To analyze the seroprevalence of SARS-CoV-2 and the association of sociodemographic and clinical aspects in the state of Espírito Santo, Brazil. Methods: Serial cross-sectional study carried out in four phases, using households as the unit of analysis, from May to June 2020. 11 municipalities were surveyed, with a sample of 4,500 households in each phase. Results: the prevalence ranged from 2.1% (95%CI: 1.7;2.5) on May 10 (first stage) to 9.6% (95%CI: 8.8;10.4), on June 21 (fourth stage). In the metropolitan region of Greater Vitória, the prevalences were 2.7% (95%CI: 2.2;3.3), in the first, and 11.5% (95%CI: 10.5;12.6) in the fourth stage; within the state it ranged from 0.4% (95%CI: 0.1;0.9) to 4.4% (95%CI: 3.2;5.5) between the two stages. Conclusion: The increase in SARS-CoV-2 seroprevalence observed in the fourth phase highlighted the high transmission of the virus, supporting the management of the pandemic.