Preprint / Version 2

Patient Blood Management PBM: an effective, safe, cost-effective and evidence-based way to provide medical treatment in the face of scarcity of blood bags caused by the COVID-19 pandemic




Blood preservation, Bloodless Medical and Surgical Procedures, Blood transfusion, Coronavirus Infections, Coronavirus


Introduction: The COVID-19 pandemic caused a significant shortage of blood stocks in several countries. Different strategies used in this scenario, such as suspension of elective surgeries, calling for more donors and loosening of regulations used in blood centers have limitations. The objective of this study was to evaluate the effectiveness, safety and cost-effectiveness of a set of medical care called Patient Blood Management (PBM) through a narrative review of the literature. Methods: Non-systematic literature search, without restriction of type of study, date or language, in the scientific databases: MEDLINE, LILACS, EMBASE, Cochrane Library, SciELO, Scopus and Web of Science. Results: Randomized clinical trials and meta-analysis of observational studies demonstrated that the use of PBM promoted a reduction in blood transfusions, length of hospital stay, complications such as acute renal failure, infection, thromboembolic events, and mortality. Economic analysis studies have observed significant savings in financial resources in the places where the PBM was implemented. Conclusion: PBM is effective, safe and cost-effective, promoting a reduction in blood transfusions, improving clinical outcomes and saving financial resources, characteristics that make it relevant in the face of a health system overburdened by the pandemic.


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Author Biographies

Antonio Alceu Santos, Hospital Beneficiência Portuguesa

MD, cardiologist.

Rafael Silva Araújo, Universidade Federal de São Paulo

Aluno do Mestrado Profissional Ciência, Tecnologia e Gestão Aplicadas à Regeneração Tecidual, Disciplina de Cirurgia Plástica, Universidade Federal de São Paulo, Rua Pedro de Toledo, 650, 2° andar, Vila Clementino, CEP: 04039-002, São Paulo, SP, Brasil

Guilherme de Castro Machado Rabello, InovaInCor - Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da USP

Gerente de Inovação do InovaInCor - Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da USP; Membro associado da Society for Advancement of Blood Management (SABM). Av, Dr Enéas de Carvalho de Aguiar, 44. Cerqueira César, CEP: 05403-900, São Paulo, SP, Brasil.


2020-05-02 — Updated on 2020-06-05



Health Sciences