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Coronavirus 2: Analysis of Regularity of Complete Genome (SARS-CoV-2/Hu/DP/Kng/19-020 RNA)

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DOI:

https://doi.org/10.1590/SciELOPreprints.29

Keywords:

Coronavirus 2, SARS-CoV-2, Complete Genome, Regularity Analysis, RNA, index of maximum regularity, Covid-19

Abstract

This paper shows a technique for the detection of regularities in the complete genome of Coronavirus 2. For this, the concept of intervals in the RNA chain and their comparison within the known sequence is used. The Maximum Regularity Index was applied. The results show that areas of high regularity are identified that coincide with ORF10, Gene N, nucleocapsid phosphoprotein and others. The interval around 3500 and the interval around 11000, respectively, appear with high values of regularity and this do not correspond to particularly documented elements (both within Gene: Orf1ab). It might be in the interest of giving importance to that region. The detection of regularities can enhance the creation of biochemical or genetic techniques to deactivate certain functions of Coronavirus 2 or control its effects.

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Posted

2020-04-11 — Updated on 2020-06-04

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Section

Biological Sciences