COVID-Inconfidentes - SARS-CoV-2 seroprevalence in two Brazilian urban areas during the pandemic first wave: study protocol and initial results

Adriana Lucia Meireles; Luciano Garcia Lourenção; Luiz Antônio Alves de Menezes Junior; Hillary Nascimento Coletro; Irene Carolina Sousa Justiniano; Samara Silva de Moura; Amanda Popolino Diniz; Thaís da Silva Sabião; Ana Maria Sampaio Rocha; Aline Priscila Batista; Nara Nunes Lage; Bárbara dos Santos Simões; Carolina Ali Santos; Raquel de Deus Mendonça; Amanda Cristina de Souza Andrade; Keila Furbino Barbosa; Cássio Zumerle Masioli; Júlia Cristina Cardoso Carraro; Mariana Carvalho de Menezes; Renata Cristina Rezende Macedo Nascimento; Leonardo Roever; Waleska Teixeira  Caiaffa; George Luiz Lins Machado-Coelho

doi:10.1590/SciELOPreprints.2720

##article.authors##

Adriana Lucia Meireles Federal University of Ouro Preto https://orcid.org/0000-0002-1447-953X
Luciano Garcia Lourenção Federal University of Ouro Preto https://orcid.org/0000-0002-1240-4702
Luiz Antônio Alves de Menezes Junior Federal University of Ouro Preto https://orcid.org/0000-0002-4497-5358
Hillary Nascimento Coletro Federal University of Ouro Preto https://orcid.org/0000-0002-9142-6079
Irene Carolina Sousa Justiniano Federal University of Ouro Preto https://orcid.org/0000-0002-1635-3367
Samara Silva de Moura Federal University of Ouro Preto https://orcid.org/0000-0003-2485-5137
Amanda Popolino Diniz Federal University of Ouro Preto
Thaís da Silva Sabião Federal University of Ouro Preto
Ana Maria Sampaio Rocha Federal University of Ouro Preto https://orcid.org/0000-0003-0665-6548
Aline Priscila Batista Federal University of Ouro Preto https://orcid.org/0000-0001-8305-1011
Nara Nunes Lage Federal University of Ouro Preto https://orcid.org/0000-0003-0243-9378
Bárbara dos Santos Simões Federal University of Ouro Preto
Carolina Ali Santos Federal University of Ouro Preto https://orcid.org/0000-0001-7237-5299
Raquel de Deus Mendonça Federal University of Ouro Preto
Amanda Cristina de Souza Andrade Federal University of Mato Grosso https://orcid.org/0000-0002-3366-4423
Keila Furbino Barbosa Federal University of Ouro Preto https://orcid.org/0000-0001-9546-8893
Cássio Zumerle Masioli Federal University of Ouro Preto
Júlia Cristina Cardoso Carraro Federal University of Ouro Preto https://orcid.org/0000-0003-0027-2690
Mariana Carvalho de Menezes Federal University of Ouro Preto https://orcid.org/0000-0002-3069-7959
Renata Cristina Rezende Macedo Nascimento Federal University of Ouro Preto https://orcid.org/0000-0001-7756-2157
Leonardo Roever Federal University of Uberlândia https://orcid.org/0000-0002-7517-5548
Waleska Teixeira Caiaffa Federal University of Minas Gerais https://orcid.org/0000-0001-5043-4980
George Luiz Lins Machado-Coelho Universidade Federal de Ouro Preto

DOI:

https://doi.org/10.1590/SciELOPreprints.2720

Keywords:

Coronavirus Infections, Pandemics, Health Surveys, Epidemiology, COVID-19 Serological Testing

Abstract

Background: A population study is an important tool that can be used to understand the actual epidemiological scenario of the Covid-19 in different territories, identify its magnitude, understand its transmission dynamics, and its demographic, geographical, and social distribution.

Objective: The aim of this study was to determine the prevalence and dynamics of SARS-CoV-2 infection in the population of two Brazilian cities during the pandemic first wave and subsequent socioeconomic and health effects.

Materials & methods: This paper described the methodological procedures adopted and the prevalence of the SARS-CoV-2 infection in the population. A household survey was conducted between October and December 2020, in two historic cities of Brazil's mining region. Anti-SARS-CoV-2 antibody was detected using the Wondfo® rapid test. The face-to-face interview consisted of administration of a questionnaire containing registration data, sociodemographic and economic variables, living habits, general health condition, mental health, sleep habits, and eating and nutrition.

Results: We evaluated 1,762 residents, of which 764 (43.4%) were in Mariana and 998 (56.6%) in Ouro Preto. For both cities, 51.9% of the interviewees were female, with a predominance of the age range 35 to 59 years old (47.2%). The prevalence of the SARS-CoV-2 infection was 5.5% in all cities, 6.2% in Ouro Preto, and 4.7% in Mariana. The prevalence was similar between cities (P>0.05).

Conclusion: The study was effective in verifying the seroprevalence of infection by the virus and its findings will enable further analyses of the health conditions of the population related to social isolation and the risk of infection with SARS-CoV-2.