Preprint / Version 1

Letter to the Scientific Community: Brazil in face of the new SARS-CoV-2 variants

##article.authors##

  • Flavia Maria Darcie Marquitti Universidade Estadual de Campinas
  • Renato Mendes Coutinho Universidade Federal do ABC
  • Leonardo Souto Ferreira Universidade Estadual Paulista
  • Marcelo Eduardo Borges Observatório Covid-19 BR
  • Tatiana P Portella Universidade de São Paulo
  • Rafael Lopes Paixão da Silva Universidade Estadual Paulista
  • Otavio Canton Universidade Estadual Paulista
  • Silas Poloni Universidade Estadual Paulista
  • Caroline Franco Universidade Estadual Paulista
  • Verônica Coelho Instituto do Coração - Faculdade de Medicina - Universidade de São Paulo
  • Lorena Barberia Universidade de São Paulo
  • Monica de Bolle Johns Hopkins University
  • Alexandra Crispim Boing Universidade Federal de Santa Catarina
  • Maria Rita Donalisio Universidade Estadual de Campinas
  • Antonio Fernando Boing Universidade Federal de Santa Catarina
  • Antônio Augusto Moura da Silva Universidade Federal do Maranhão
  • Paulo Inácio Prado Universidade de São Paulo
  • Maria Amélia de Sousa Mascena Veras Faculdade de Ciências Médicas da Santa Casa de São Paulo
  • Roberto Kraenkel Universidade Estadual Paulista https://orcid.org/0000-0001-5602-5184

DOI:

https://doi.org/10.1590/SciELOPreprints.2001

Keywords:

Covid-19, vigilance, p1

Abstract

This letter discusses the epidemic situation of Covid-19 in Brazil, in the face of the emergence of a new strain, called P1, more transmissible and with possible associated reinfection.  Given the collapse of hospital care in Manaus in January 2021 and the results of three recent preprints, all of which found increased transmissibility of the P.1 variant, we propose some urgent actions: the establishment of genomic surveillance based on multi-step diagnostics, starting with RT-PCR type tests  to sequencing; an immediate effort to identify reinfections associated with the new variant, updating its definition protocols; and studies on the efficacy of currently available vaccines in Brazil in respect to the new variant.  We also propose the improvement of the Brazilian health surveillance system, which should be articulated with genomic surveillance, in order to respond more timely to future emergencies. We call on the public agents involved in health surveillance to share data and information regarding the epidemic in a clear, fast and transparent way. Finally, we propose a greater engagement in inter-institutional cooperation of all those involved in the response and production of knowledge about the pandemic in our country.

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Posted

2021-03-23

Section

Health Sciences