COVID-19: Implications for People with Chagas Disease
Keywords:Chagas disease, COVID-19, neglected tropical diseases (NTDs)
As the global COVID-19 pandemic advances, it increasingly impacts the vulnerable populations who already bear a heavy burden of neglected tropical diseases. Chagas disease (CD), a neglected parasitic infection, is of particular concern because of its potential to cause cardiac, gastrointestinal, and other complications which could increase susceptibility to COVID-19. The over one million people worldwide with chronic Chagas cardiomyopathy require special consideration because of COVID-19’s potential impact on the heart, yet the pandemic also affects treatment provision to people with acute or chronic indeterminate CD. In this document, a follow-up to the WHF-IASC Roadmap on CD, we assess the implications of coinfection with SARS-CoV-2 and Trypanosoma cruzi, the etiological agent of CD. Based on the limited evidence available, we provide preliminary guidance for testing, treatment, and management of patients affected by both diseases, while highlighting emerging healthcare access challenges and future research needs.
Copyright (c) 2020 Ezequiel Zaidel, Colin Forsyth, Gabriel Novick, Rachel Marcus, Antonio Luiz Ribeiro, Maria Jesus Pinazo, Carlos Morillo, Luis Eduardo Echeverria, Maria Aparecida Shikanai-Yasuda, Pierre Buekens, Pablo Perel, Sheba Meymandi, Kate Ralston, Fausto Pinto, Sergio Sosa-Estani
This work is licensed under a Creative Commons Attribution 4.0 International License.